Todd Castoe,
Professor, Department of Biology
Genome biology, gene regulatory networks, population genomics: The Castoe laboratory studies genome biology and evolutionary genomics using integrative approaches and vertebrates and invertebrate parasites as model systems. Research in the laboratory addresses fundamental questions in genome biology and evolution including how novel gene regulatory networks arise and co-opt existing signaling pathways, how single-cell heterogeneity manifests in organism-level phenotypes, how vertebrates control regenerative growth, how multiple synergistic processes shape genome structure and function, and how synergistic evolutionary processes operating on the genome result in speciation.
Jeffery Demuth,
Associate Professor, Department of Biology
Bioinformatics: My group uses a variety of molecular and computational approaches to study the evolution of genes, genomes and organisms. Central themes of our work include genome organization, sex chromosome regulation and evolution, and behavioral genetics. Recent efforts have been particularly focused on leveraging advances in our capacity to interrogate high-throughput single-cell data to provide unprecedented resolution into.